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1

IL-1? and IFN-? induce the regenerative epidermal phenotype of psoriasis in the transwell skin organ culture system. IFN-? up-regulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL-1 production

Wei, Liu, Debets, Reno, Hegmans, Joost J, Benner, Robbert, Prens, Errol P.

Journal:

The Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 542 KB

english, 1999

2

Enhanced production of biologically active interleukin-1α and interleukin-1β by psoriatic epidermal cells ex vivo: evidence of increased cytosolic interleukin-1β levels and facilitated interleukin-1 release

Reno Debets, Joost P. J. J. Hegmans, Roger J. J. Troost, Robbert Benner, Errol P. Prens

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 780 KB

english, 1995

3

Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines

Claudia Zanazzi, Remko Hersmus, Imke M. Veltman, Ad J.M. Gillis, Ellen van Drunen, H. Berna Beverloo, Joost P.J.J. Hegmans, Marielle Verweij, Bart N. Lambrecht, J. Wolter Oosterhuis, Leendert H.J. Loo

Journal:

Genes, Chromosomes and Cancer

Year:

2007

Language:

english

File:

PDF, 720 KB

english, 2007

4

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

Joris D Veltman, Margaretha EH Lambers, Menno van Nimwegen, Rudi W Hendriks, Henk C Hoogsteden, Joachim GJV Aerts, Joost PJJ Hegmans

Journal:

Year:

2010

Language:

english

File:

PDF, 6.64 MB

english, 2010

5

Expression of cytokines and their receptors by psoriatic fibroblasts I.: Altered IL-6 synthesis

Reno Debets, Joost P.J.J. Hegmans, Mette Deleuran, Sinka 't Hooft, Robbert Benner, Errol P. Prens

Journal:

Year:

1996

Language:

english

File:

PDF, 140 KB

english, 1996

6

Expression of cytokines and their receptors by psoriatic fibroblasts. II.: Decreased TNF receptor expression

Reno Debets, Joosts P.J.J. Hegmans, Wim A. Buurman, Robbert Benner, Errol P. Prens

Journal:

Year:

1996

Language:

english

File:

PDF, 122 KB

english, 1996

7

T lymphocytes in psoriasis

Errol Prens, Reno Debets, Joost Hegmans

Journal:

Clinics in Dermatology

Year:

1995

Language:

english

File:

PDF, 2.37 MB

english, 1995

8

Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B

Eric T.T.L. Tjwa, Gertine W. van Oord, Joost P. Hegmans, Harry L.A. Janssen, Andrea M. Woltman

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

9

Proteomic Analysis of Exosomes Secreted by Human Mesothelioma Cells

Joost P.J.J. Hegmans, Martin P.L. Bard, Annabrita Hemmes, Theo M. Luider, Monique J. Kleijmeer, Jan-Bas Prins, Laurence Zitvogel, Sjaak A. Burgers, Henk C. Hoogsteden, Bart N. Lambrecht

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

10

History of tuberculosis as an independent prognostic factor for lung cancer survival

Heuvers, Marlies E., Aerts, Joachim G.J.V., Hegmans, Joost P., Veltman, Joris D., Uitterlinden, André G., Ruiter, Rikje, Rodenburg, Eline M., Hofman, Albert, Bakker, Marleen, Hoogsteden, Henk C., Stri

Journal:

Year:

2012

Language:

english

File:

PDF, 248 KB

english, 2012

11

Differential regulation of IL-1α, IL-1ra, and IL-1R2 by IL-1β stimulation in a skin organ culture model

Wei, Liu, Vooys, André, Debets, Reno, Hegmans, Joost, Benner, Robbert, Prens, Errol

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

12

Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment

Marlies E Heuvers, Joachim G Aerts, Robin Cornelissen, Harry Groen, Henk C Hoogsteden, Joost P Hegmans

Journal:

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

13

Improving lung cancer survival; time to move on

Marlies E Heuvers, Joost P Hegmans, Bruno H Stricker…

Journal:

BMC Pulmonary Medicine

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

14

Consolidative Dendritic Cell-based Immunotherapy Elicits Cytotoxicity against Malignant Mesothelioma

Hegmans, Joost P., Veltman, Joris D., Lambers, Margaretha E., de Vries, I. Jolanda M., Figdor, Carl G., W. Hendriks, Rudi, Hoogsteden, Henk C., Lambrecht, Bart N., Aerts, Joachim G.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

15

Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients

Heuvers, Marlies E., Muskens, Femke, Bezemer, Koen, Lambers, Margaretha, Dingemans, Anne-Marie C., Groen, Harry J.M., Smit, Egbert F., Hoogsteden, Henk C., Hegmans, Joost P.J.J., Aerts, Joachim G.J.V.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

16

Proteomic Analysis of Exosomes Isolated from Human Malignant Pleural Effusions

Bard, Martin P., Hegmans, Joost P., Hemmes, Annabrita, Luider, Theo M., Willemsen, Rob, Severijnen, Lies-Anne A., van Meerbeeck, Jan P., Burgers, Sjaak A., Hoogsteden, Henk C., Lambrecht, Bart N.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

17

Biomarkers for immune checkpoint inhibitors

Lievense, Lysanne A, Hegmans, Joost P J J, Aerts, Joachim G J V

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

18

Immunomodulation in cancer

Hegmans, Joost PJJ, Aerts, Joachim GJV

Journal:

Current Opinion in Pharmacology

Year:

2014

Language:

english

File:

PDF, 853 KB

english, 2014

19

Immunological profiling as a means to invigorate personalized cancer therapy

Hegmans, Joost PJJ, Aerts, Joachim GJV

Journal:

Year:

2013

Language:

english

File:

PDF, 309 KB

english, 2013

20

Intratumoral macrophage phenotype and CD8+ T lymphocytes as potential tools to predict local tumor outgrowth at the intervention site in malignant pleural mesothelioma

Cornelissen, Robin, Lievense, Lysanne A., Robertus, Jan-Lukas, Hendriks, Rudi W., Hoogsteden, Henk C., Hegmans, Joost P.J.J., Aerts, Joachim G.J.V.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.43 MB

english, 2015

21

Low-Dose Cyclophosphamide Synergizes with Dendritic Cell-Based Immunotherapy in Antitumor Activity

Veltman, Joris D., Lambers, Margaretha E. H., van Nimwegen, Menno, de Jong, Sanne, Hendriks, Rudi W., Hoogsteden, Henk C., Aerts, Joachim G. J. V., Hegmans, Joost P. J. J.

Journal:

Journal of Biomedicine and Biotechnology

Year:

2010

Language:

english

File:

PDF, 638 KB

english, 2010

22

TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets

Straetemans, Trudy, van Brakel, Mandy, van Steenbergen, Sabine, Broertjes, Marieke, Drexhage, Joost, Hegmans, Joost, Lambrecht, Bart N., Lamers, Cor, Bruggen, Pierre van Der, Coulie, Pierre G., Debets

Journal:

Clinical & Developmental Immunology

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

23

Immunoglobulin-like transcript 3 is expressed by myeloid-derived suppressor cells and correlates with survival in patients with non-small cell lung cancer

de Goeje, Pauline L, Bezemer, Koen, Heuvers, Marlies E, Dingemans, Anne-Marie C, Groen, Harry Jm, Smit, Egbert F, Hoogsteden, Henk C, Hendriks, Rudi W, Aerts, Joachim Gjv, Hegmans, Joost Pjj

Journal:

Year:

2015

Language:

english

File:

PDF, 980 KB

english, 2015

24

Immunotherapy of Murine Malignant Mesothelioma Using Tumor Lysate–pulsed Dendritic Cells

Hegmans, Joost P. J. J., Hemmes, Annabrita, Aerts, Joachim G., Hoogsteden, Henk C., Lambrecht, Bart N.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 313 KB

english, 2005

25

Extended Tumor Control After Dendritic Cell Vaccination With Low Dose Cyclophosphamide as Adjuvant Treatment in Patients With Malignant Pleural Mesothelioma

Cornelissen, Robin, Hegmans, Joost P. J. J., Maat, Alexander P. W. M., Kaijen-Lambers, Margaretha E. H., Bezemer, Koen, Hendriks, Rudi W, Hoogsteden, Henk C, Aerts, Joachim G. J. V.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 1.80 MB

english, 2015

26

Expression Profiling-Based Subtyping Identifies Novel Non-small Cell Lung Cancer Subgroups and Implicates Putative Resistance to Pemetrexed Therapy

Hou, Jun, Lambers, Margaretha, den Hamer, Bianca, den Bakker, Michael A., Hoogsteden, Henk C., Grosveld, Frank, Hegmans, Joost, Aerts, Joachim, Philipsen, Sjaak

Journal:

Journal of Thoracic Oncology

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

27

Precision immunotherapy; dynamics in the cellular profile of pleural effusions in malignant mesothelioma patients

Lievense, Lysanne A., Bezemer, Koen, Cornelissen, Robin, Kaijen-Lambers, Margaretha E.H., Hegmans, Joost P.J.J., Aerts, Joachim G.J.V.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

28

Pleural Effusion of Patients with Malignant Mesothelioma Induces Macrophage-Mediated T Cell Suppression

Lievense, Lysanne A., Cornelissen, Robin, Bezemer, Koen, Kaijen-Lambers, Margaretha E.H., Hegmans, Joost P.J.J., Aerts, Joachim G.J.V.

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 892 KB

english, 2016

29

Dendritic cell-based immunotherapy in mesothelioma

Cornelissen, Robin, Lievense, Lysanne A, Heuvers, Marlies E, Maat, Alexander P, Hendriks, Rudi W, Hoogsteden, Henk C, Hegmans, Joost P, Aerts, Joachim G

Journal:

Year:

2012

Language:

english

File:

PDF, 721 KB

english, 2012

30

Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma

Mahaweni, Niken M., Kaijen-Lambers, Margaretha E.H., Dekkers, Jacqueline, Aerts, Joachim G.J.V., Hegmans, Joost P.J.J.

Journal:

Journal of Extracellular Vesicles

Year:

2013

Language:

english

File:

PDF, 964 KB

english, 2013

31

OA13.06 Autologous Dendritic Cells Loaded with Allogeneic Tumor Cell Lysate (Pheralys®) in Patients with Mesothelioma: Final Results of a Phase I Study

Aerts, Joachim, Cornelissen, Robin, Van Der Leest, Cor, Hegmans, Joost, Bezemer, Koen, Kaijen-Lambers, Margaretha, Eskens, Ferry, Braakman, Eric, Van Der Holt, Bronno, Hendriks, Rudi, Hoogsteden, Henk

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 93 KB

english, 2017

32

Depletion of tumor-associated macrophages with a CSF-1R kinase inhibitor enhances antitumor immunity and survival induced by DC immunotherapy

Dammeijer, Floris, Lievense, Lysanne A., Kaijen-Lambers, Margaretha E H, van Nimwegen, Menno, Bezemer, Koen, Hegmans, Joost P, van Hall, Thorbald, Hendriks, Rudi W, Aerts, Joachim G.

Journal:

Cancer Immunology Research

Year:

2017

Language:

english

File:

PDF, 11.38 MB

english, 2017

33

Ratio of Intratumoral Macrophage Phenotypes Is a Prognostic Factor in Epithelioid Malignant Pleural Mesothelioma

Cornelissen, Robin, Lievense, Lysanne A., Maat, Alexander P., Hendriks, Rudi W., Hoogsteden, Henk C., Bogers, Ad J., Hegmans, Joost P., Aerts, Joachim G., Gangopadhyay, Nupur

Journal:

Year:

2014

Language:

english

File:

PDF, 852 KB

english, 2014

34

Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy

Noordam, Lisanne, Kaijen, Margaretha. E.H., Bezemer, Koen, Cornelissen, Robin, Maat, Lex A.P.W.M., Hoogsteden, Henk C., Aerts, Joachim G.J.V., Hendriks, Rudi W., Hegmans, Joost P.J.J, Vroman, Heleen

Journal:

Year:

2018

Language:

english

File:

PDF, 3.78 MB

english, 2018

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